Which NSAIDs cause hypertension?
Among nonselective NSAIDs, ibuprofen increases the risk of hypertension and stroke.
Why are NSAIDs contraindicated in hypertension?
However, NSAIDs can make your body retain fluid and decrease the function of your kidneys. This may cause your blood pressure to rise even higher, putting greater stress on your heart and kidneys. NSAIDs can also raise your risk for heart attack or stroke, especially in higher doses.
How does NSAIDs induce an increase in blood pressure?
NSAIDs also inhibit the vasodilating effects of prostaglandins and the production of vasoconstricting factors—namely, endothelin-1. These effects can contribute to the induction of hypertension in a normotensive or controlled hypertensive patient.
Can NSAIDs worsen hypertension?
All nonsteroidal antiinflammatory drugs (NSAIDs) in doses adequate to reduce inflammation and pain can increase blood pressure in both normotensive and hypertensive individuals [1].
Which NSAID is safe for hypertension?
Aspirin is also an NSAID, but experts think that it’s safer for people with hypertension. Acetaminophen — the active ingredient in Tylenol — is a different type of painkiller that doesn’t raise blood pressure as a side effect.
Which NSAID has least effect on blood pressure?
Naproxen (Naprosyn) does not increase the risk of hypertension or stroke. Celecoxib (Celebrex) does not increase the risk of hypertension or stroke.
Which NSAID is best for hypertension?
Why diclofenac is contraindicated in hypertension?
Diclofenac may decrease the blood pressure-lowering effects of some drugs used to control blood pressure. Using diclofenac with certain blood pressure medications may also increase your risk of kidney damage.
Can a hypertensive patient take ibuprofen?
Unless your doctor has told you it’s OK, do not use over-the-counter ibuprofen, naproxen sodium, or ketoprofen for pain relief. Instead, use a painkiller less likely to increase your blood pressure, like aspirin or acetaminophen.
Can I take ibuprofen with high blood pressure?
NSAIDs like ibuprofen (e.g. Advil®, MOTRIN®) and naproxen sodium (e.g. Aleve®) can produce several effects on your body that may further worsen high blood pressure. NSAIDs can: Impact sodium and water retention in the kidneys. Increase resistance of blood vessels (constricts blood flow), which can raise blood pressure.
Can I take naproxen if I have high blood pressure?
But it turns out, they come with plenty of risks — especially for people with high blood pressure. The American Heart Association (AHA) has long recommended acetaminophen (Tylenol) as a safe alternative to nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve).