Are testicular germ cell tumors malignant?
Most malignant testicular neoplasms are of germ cell origin. They are divided into five basic types: seminomas, embryonal carcinomas, teratocarcinomas, adult teratomas and choriocarcinomas. Clinically they may present as an enlarging testicular mass, or with symptoms resulting from metastases or hormonal secretions.
What is mixed malignant germ cell tumor?
Malignant mixed germ cell tumor is a type of tumor that consists of two or more malignant germ cell components. These tumors are quite rare cancers, seen in 8% cases of germ cell tumors but are very aggressive in nature (5).
Are mixed germ cell tumors cancerous?
A rare type of cancer that is made up of at least two different types of germ cell tumors (tumors that begin in cells that form sperm or eggs). These may include choriocarcinoma, embryonal carcinoma, yolk sac tumor, teratoma, and seminoma.
Can germ cell tumor be cured?
Germ cell tumors that occur in places other than the testicles and ovaries (extragonadal germ cell tumors) are very rare. Treatment options for germ cell tumors may include surgery to remove the tumor, chemotherapy with drugs that kill cancer cells and radiation therapy with powerful energy beams.
What is the most common germ cell tumor of testis?
The most common type of testis cancer is a germ cell tumor. There are two main types of GCT: seminoma and nonseminomatous germ cell tumors (NSGCT). Both seminoma and NSGCT occur at about the same rate, and men can have seminoma, NSGCT or a combination of both.
What is testicular germ cell tumor?
More than 90% of testicular cancer start in the germ cells, which are cells in the testicles and develop into sperm. This type of cancer is known as testicular germ cell cancer. Testicular germ cell cancer can be classified as either seminomas or nonseminomas, which may be identified by microscopy.
What is the difference between benign and malignant tumors?
A benign tumor has distinct, smooth, regular borders. A malignant tumor has irregular borders and grows faster than a benign tumor. A malignant tumor can also spread to other parts of your body. A benign tumor can become quite large, but it will not invade nearby tissue or spread to other parts of your body.
What causes a mixed germ cell tumor?
Doctors aren’t sure what triggers that change. Still, you may be more likely to a germ cell tumor if you have: An undescended testicle (one or both testicles haven’t dropped into the scrotum) Birth defects in your central nervous system, genitals, lower spine, and urinary tract.
Do malignant tumors grow fast?
Malignant tumours are made up of cancer cells. They: usually grow faster than benign tumours.
What causes a germ cell tumor?
– a tumor, swelling or mass that can be seen or felt – constipation, incontinence and leg weakness if the tumor is located in the pelvis or abdomen – shortness of breath if the tumor is located in the chest – elevated levels of certain proteins secreted by the tumors into the blood
What is the prognosis for malignant germ cell tumor?
The outlook for malignant germ cell tumors varies depending on how far the cancer has spread. Cancer specialists measure cancer outlook by the five-year survival rate. If cancer hasn’t spread to other parts of the body, there is a 94% to 98% survival rate.
What are the symptoms of germ cell cancer?
Pelvic pain or tenderness: Pelvic discomfort,cramping and ovarian pain are common symptoms of germ cell tumors.
What is mixed germ cell cancer?
The main types of germ cell tumors (GCTs) in the testicles are seminomas and non-seminomas. These types occur about equally. Many testicular cancers contain both seminoma and non-seminoma cells. These mixed germ cell tumors are treated as non-seminomas because they grow and spread like non-seminomas.
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