Why is metabolic pool significant?
The concept of metabolic pool is significant in cell biology because it allows one type of molecule to change into another type E.g. Carbohydrates can be converted to fats and vice-versa.
What is the concept of metabolic pools?
Metabolite pool is a collective term for all of the substances involved in the metabolic process in a biological system. Metabolic pools are within cells (or organelles such as chloroplasts) and refer to the reservoir of molecules upon which enzymes can operate.
How metabolic pool is formed in the cell?
The metabolic pool in the cell is formed due to glycolysis and Krebs cycle. The catabolic chemical reaction of glycolysis and Krebs cycle provides ATP and biomolecules. These biomolecules form the metabolic pool of the cell. These biomolecules can be utilized for the synthesis of many important cellular components.
What is flux biochemistry?
Flux, or metabolic flux is the rate of turnover of molecules through a metabolic pathway. Flux is regulated by the enzymes involved in a pathway. Within cells, regulation of flux is vital for all metabolic pathways to regulate the pathway’s activity under different conditions.
How does caspase cause cell death?
Apoptosis is mediated by proteolytic enzymes called caspases, which trigger cell death by cleaving specific proteins in the cytoplasm and nucleus. Caspases exist in all cells as inactive precursors, or procaspases, which are usually activated by cleavage by other caspases, producing a proteolytic caspase cascade.
What is metabolism how metabolic food is formed in the cell?
metabolism, the sum of the chemical reactions that take place within each cell of a living organism and that provide energy for vital processes and for synthesizing new organic material.
What affects metabolic flux?
In order to understand the complex regulation of metabolic fluxes, one can specify the flux through a given biochemical reaction as a function of three factors: (i) the activity level of the enzyme catalyzing the reaction; (ii) the properties of the enzyme (i.e., its affinities for the substrates and possible affectors …
What is meant by metabolic flux?
Metabolic flux refers to the amount of a metabolite processed by one or more catalytic steps per unit time, and it is typically normalized by cellular abundance (e.g., gram dry weight) (Stephanopoulos et al., 1998).
Why are caspases called caspases?
They are named Caspases due to their specific cysteine protease activity – a cysteine in its active site nucleophilically attacks and cleaves a target protein only at the C-terminal of an aspartic acid amino acid.
Why are caspases important in apoptosis?
Abstract. Caspases are crucial mediators of programmed cell death (apoptosis). Among them, caspase-3 is a frequently activated death protease, catalyzing the specific cleavage of many key cellular proteins.
What is acidosis and what causes it?
Acidosis occurs when your kidneys and lungs can’t keep your body’s pH in balance. Many of the body’s processes produce acid. Your lungs and kidneys can usually compensate for slight pH imbalances, but problems with these organs can lead to excess acid accumulating in your body. The acidity of your blood is measured by determining its pH.
What causes Hyperchloremic acidosis?
If your body lacks enough insulin, ketones build up in your body and acidify your blood. Hyperchloremic acidosis results from a loss of sodium bicarbonate. This base helps to keep the blood neutral. Both diarrhea and vomiting can cause this type of acidosis.
What are the treatment options for metabolic acidosis?
The specific types of metabolic acidosis each have their own treatments. People with hyperchloremic acidosis may be given oral sodium bicarbonate. Acidosis from kidney failure may be treated with sodium citrate. Diabetics with ketoacidosis receive IV fluids and insulin to balance out their pH.
What are the different types of acidosis?
There are two types of acidosis, each with various causes. The type of acidosis is categorized as either respiratory acidosis or metabolic acidosis, depending on the primary cause of your acidosis. Respiratory acidosis occurs when too much CO2 builds up in the body. Normally, the lungs remove CO2 while you breathe.