What is IV cefepime used to treat?
Cefepime injection is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth.
What is the indication for cefepime?
Cefepime for Injection is indicated in the treatment of uncomplicated and complicated urinary tract infections (including pyelonephritis) caused by susceptible isolates of Escherichia coli or Klebsiella pneumoniae, when the infection is severe, or caused by Escherichia coli, Klebsiella pneumoniae, or Proteus mirabilis.
What infections does cefepime treat?
Cefepime injection is used to treat certain infections caused by bacteria including pneumonia, and skin, urinary tract, and kidney infections. Cefepime injection is used in combination with metronidazole (Flagyl) to treat abdominal (stomach area) infections.
What is the action of cefepime?
Cefepime is used to treat a wide variety of bacterial infections. This medication belongs to a class of drugs known as cephalosporin antibiotics. It works by stopping the growth of bacteria.
Is cefepime used to treat sepsis?
The majority of broad-spectrum agents administered for sepsis have activity against Gram-positive organisms such as methicillin-susceptible Staphylococcus aureus, or MSSA, and Streptococcal species. This includes the antibiotics piperacillin/tazobactam, ceftriaxone, cefepime, meropenem, and imipenem/cilastatin.
Does cefepime cover UTI?
In these studies a favorable clinical and microbiologic response was observed in >95% of cefepime-treated and ceftazidime-treated children assessed at the end of treatment. Conclusions: These results indicate that cefepime represents an important therapeutic option for the treatment of serious UTIs in children.
What bacteria does cefepime not cover?
Comparison of the 3 broadest spectrum beta-lactams: Cefepime, Zosyn, and Carbapenems (non-Ertapenem) have activity against both Gram positive (MSSA, Strep) and Gram negative including Pseudomonas. They do NOT cover: MRSA, VRE, Atypicals, among others.
Which antibiotic is given first for sepsis?
What is the strongest antibiotic for sepsis?
What is the best medication for sepsis?
| Best medications for sepsis | ||
|---|---|---|
| Vancomycin | Antibiotic | Intravenous injection |
| Rocephin (ceftriaxone) | Antibiotic | Intravenous injection |
| Zosyn (piperacillin-tazobactam) | Antibiotic | Intravenous injection |
| Cefepime | Antibiotic | Intravenous injection |
Will cefepime cover E coli?
Selections of bacteria susceptible to cefepime are as follows: Streptococcus pneumoniae, Klebsiella pneumoniae, Enterobacter group, Haemophilus influenza, Pseudomonas aeruginosa, Escherichia coli, Proteus mirabilis, Streptococcus pyogenes, methicillin-susceptible Staphylococcus aureus, Streptococci viridans species.
Does cefepime treat MRSA?
Cefepime has broad-spectrum activity against gram-negative and gram-positive organisms. We have previously demonstrated that the combination of cefepime with vancomycin, linezolid, or quinupristin-dalfopristin had an improved or enhanced effect against methicillin-resistant Staphylococcus aureus (MRSA).
Does cefepime Cover Staph aureus?
Cefepime is a new injectable cephalosporin with a broad spectrum of activity against many gram-positive and gram- negative bacteria, including Staphylococcus aureus and Pseudo- monas aeruginosa.
What is the indication of cefepime for injection as monotherapy?
Cefepime for Injection as monotherapy is indicated for empiric treatment of febrile neutropenic patients. In patients at high risk for severe infection (including patients with a history of recent bone marrow transplantation, with hypotension at presentation, with an underlying hematologic malignancy,…
What is the dosage for cefepime?
Cefepime Dosage and Administration. Constitute Cefepime for injection vials 1 gram and 2 grams with one of the following diluents: Sterile Water for Injection, 0.9% Sodium Chloride, 5% Dextrose Injection, 0.5% or 1% Lidocaine Hydrochloride, or Sterile Bacteriostatic Water for Injection with Parabens or Benzyl Alcohol.
What is cefepime used to treat?
Indications and Usage for Cefepime. Pneumonia. Cefepime is indicated in the treatment of pneumonia (moderate to severe) caused by susceptible strains of Streptococcus pneumoniae, including cases associated with concurrent bacteremia, Pseudomonas aeruginosa, Klebsiella pneumoniae, or Enterobacter species.
What are the possible adverse effects of cefepime?
Serious adverse events have occurred in geriatric patients with renal insufficiency given unadjusted doses of Cefepime, including life-threatening or fatal occurrences of the following: encephalopathy, myoclonus, and seizures [see Warnings and Precautions (5.2), Adverse Reactions (6.2)].