What drugs interact with theophylline?
| Drug | Type of interaction |
|---|---|
| Allopurinol | Decreases theophylline clearance at allopurinol doses ≥600 mg/day |
| Aminoglutethimide | Increases theophylline clearance by induction of microsomal enzyme activity |
| Carbamazepine | Similar to aminoglutethimide |
| Cimetidine | Decreases theophylline clearance by inhibiting cytochrome P450 1A2 |
What drugs affect theophylline levels?
Administration of allopurinol, oral contraceptives, cimetidine, erythromycin, quinolone antibiotics, fluvoxamine, zileuton, and zafirlukast has been shown to increase theophylline levels.
What is contraindicated with theophylline?
Theophylline is contraindicated if the patient previously developed a hypersensitivity reaction to the drug or any component of its formulation (such as an allergy to corn-related products (in injection use only).
What does theophylline react with?
Other medications can affect the removal of theophylline from your body, which may affect how theophylline works. Examples include cimetidine, disulfiram, fluvoxamine, interferon, mexiletine, propranolol, rifampin, drugs used to treat seizures (such as carbamazepine, phenytoin), St.
Does ciprofloxacin interact with theophylline?
Interactions between your drugs Ciprofloxacin may significantly increase the blood levels of theophylline, which may lead to potentially serious and life-threatening side effects.
Which medications can increase the risk of theophylline toxicity?
Causes of chronic theophylline toxicity include the following: Drug interactions (eg, ethanol [ETOH], cimetidine, oral contraceptives, allopurinol, macrolide antibiotics, quinolone antibiotics)
Can Salbutamol and theophylline be taken together?
SALBUTAMOL+THEOPHYLLINE does not have any reported interaction; hence, if you experience any difficulty, discuss with your doctor.
Is theophylline contraindicated in pregnancy?
Beclomethasone has also been used extensively during pregnancy. Theophylline — Theophylline (Slo-bid, Theo-Dur, and others) has been used for many years during pregnancy without any apparent complications, suggesting that it is safe during pregnancy.
Why ciprofloxacin is contraindicated with theophylline?
ciprofloxacin theophylline Ciprofloxacin may significantly increase the blood levels of theophylline, which may lead to potentially serious and life-threatening side effects.
Can I take theophylline with erythromycin?
Using erythromycin together with theophylline may increase the effects of theophylline. You should contact your doctor if you experience nausea, vomiting, diarrhea, headache, restlessness, insomnia, seizures, or an irregular heartbeat. You may need a dose adjustment or special test to safely use both medications.
Why is there a toxic interaction between theophylline and Erythromycin?
Interactions between your drugs Using erythromycin together with theophylline may increase the effects of theophylline. You should contact your doctor if you experience nausea, vomiting, diarrhea, headache, restlessness, insomnia, seizures, or an irregular heartbeat.
What is the antidote of theophylline?
Esmolol, a short-acting beta-blocker, has been used successfully for unstable supraventricular tachycardia and related hypotension in theophylline overdose.
Does caffeine interact with theophylline?
When these two medicines are taken together, theophylline and medicines related to theophylline, including caffeine, may increase the amount of lithium output in your urine. This may lead to a decrease in amount of lithium in your blood. A decrease in the beneficial effects of lithium may occur.
What drugs cause drug interactions?
Some of the common and well-known drug-drug interactions are listed below: 1. Angiotensin Converting Enzymes (ACE) inhibitors and Potassium Supplements ACE inhibitors: ACE inhibitors are used to control blood pressure, and treat heart failure and early kidney disease. Examples include benazepril, lisinopril and enalapril
What are the three types of drug interactions?
– Pharmaceutical interactions – Pharmacokinetic interactions – Absorption – Distribution (protein binding, tissue binding) – Metabolism (hepatic, nonhepatic) – Excretion (renal, nonrenal) – Pharmacodynamic interactions (direct, indirect)
What are examples of drug interactions?
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