What do you mean by Perkin reaction?
Definition of Perkin reaction : a reaction for making an unsaturated aromatic acid (as cinnamic acid) by heating an aromatic aldehyde with an acid anhydride (as acetic anhydride) in the presence of a base (as sodium acetate or potassium carbonate)
What is the condition for Perkin reaction?
The Perkin reaction is an organic reaction developed by English chemist William Henry Perkin that is used to make cinnamic acids….
| Perkin reaction | |
|---|---|
| Reaction type | Condensation reaction |
| Reaction | |
| Aromatic aldehyde + Aliphatic Acid anhydride + Alkali salt of the acid ↓ Cinnamic acid derivatives |
What are the applications of Perkin reaction?
Applications of Perkin Reaction Mechanism Perkin Condensation is used for the synthesis of cinnamic acid in laboratories. Cinnamic acids are naturally occurring unsaturated aromatic carboxylic acids that are found commonly in cinnamon and shea butter.
Is the product of Perkin reaction?
In Perkin reaction, an aromatic aldehyde condenses with acid anhydride in the presence of sodium salt of acid (from which acid anhydride is derived) to form β-aryl-α,β-unsaturated acid.
How is cinnamic acid produced?
It is obtained from oil of cinnamon, or from balsams such as storax. It is also found in shea butter. Cinnamic acid has a honey-like odor; it and its more volatile ethyl ester (ethyl cinnamate) are flavor components in the essential oil of cinnamon, in which related cinnamaldehyde is the major constituent.
What is cinnamic acid used for?
trans-Cinnamic acid is used in the manufacture of flavors, dyes, and pharmaceuticals; but its major use is for the production of its methyl, ethyl, and benzyl esters. These esters are important components of perfumes. The acid is also a precursor to the sweetener aspartame.
What is a cinnamic acid Perkin reaction?
Before going into the details of Perkin reaction, we need to know what a cinnamic acid is and what an aldol condensation reaction is. Cinnamic acids are carboxylic acids that occur naturally and can be found in things like cinnamon (as the name would suggest) and shea butter.
What is the mechanism of Perkin reaction?
This reaction yields an α, β -unsaturated aromatic acid. Perkin reaction mechanism includes the reaction between aromatic aldehydes, the aliphatic acid anhydride, and the alkali salt of the acid to give cinnamic acid derivatives. The Perkin reaction is an organic chemical reaction named after its discoverer – William Henry Perkin.
What are the catalysts used in the Perkin reaction?
Q2: What catalysts are used in the Perkin reaction? A2: The alkali salt of the acid anhydride is used as a catalyst. However, other bases can be used for this purpose. Q3: What are the applications of this named reaction? A3: This reaction is used for the synthesis of phytoestrogenic stilbene resveratrol in the laboratory.
How do you make cinnamic acid from aromatic aldehyde?
The reaction belongs to the Carbonyl compounds and is used to make ɑ-, and β-unsaturated aromatic acids. Perkin used this reaction to make cinnamic acids. When an acid anhydride and aromatic aldehyde react with each other in the presence of a weak base, they condense to give the desired product.